Grierson-Gopalan syndrome is generally called burning feet syndrome. It is a medical situation that occurs due to some metabolic disorders or infections. This sensation causes severe aches in the feet.

This burning sensation becomes more severe at night and remains a little cool during the daytime. When Grierson-Gopalan syndrome increases, it covers not only the feet but the ankles, toes, and lower part of the leg. 

Many people often get confused when they have this type of burning sensation in their feet. They consider it due to harassment or a hectic day, but this may not always be the case.

So, whenever you feel such a sensation, make sure you contact any doctor. However, we have brought you the details of this syndrome that will help you know about it more clearly. 

What Is Grierson-Gopalan Syndrome?

As mentioned above, it is also known as burning feet syndrome. It is a condition in which the feet of a person become uncomfortably warm and severe pain starts happening in the feet.

In Grierson-Gopalan syndrome, symptoms are easy to catch and they may vary from normal to severe depending on the person’s condition.  

Grierson-Gopalan syndrome requires specific treatment. Grierson-Gopalan syndrome is also followed by excessive sweating. If this syndrome is not treated well at a given time, it may even affect your eyes. This condition is often seen in women or people between the age of 30 to 40 years. 

Symptoms Of Grierson Gopalan Syndrome:

Burning feet can be caused due to several reasons. And if you are worried about how to know about Grierson-Gopalan syndrome beforehand, you must keep certain things in mind. Generally, when burning feet syndrome happens to someone, it gives out different signs that we often ignore due to our careless behavior. 

And Grierson-Gopalan syndrome may lead to some unfortunate conditions. So, if you want not to land in such a critical condition, you must know about the symptoms of Grierson Gopalan syndrome. Here are some of its symptoms: 

  • Burning sensation in the feet ( most common) 
  • Severe aching mostly at night. 
  • Itching in the skin 
  • Redness of feet and skin
  • Sharp pain in legs and toes
  • Numbness in legs, ankles, and feet
  • Hypersensitiveness
  • Excessive sweating 
  • Tingling feeling or the sensation of a pinch or needles 

Causes Of Burning Feet: 

The above-mentioned symptoms may lead to serious disorders or eye damage, if not treated well. If you want to stay away from such kinds of disorders, you must know their root cause first. You should understand the fact how Grierson-Gopalan syndrome is caused and occurs in human beings. 

Metabolic disorders: 

It can be due to an underactive thyroid condition or in people suffering from type 1 or 2 diabetes. The interactive thyroid gland mainly causes the sensation of burning and severe pain in the feet followed by fatigue, weight gain, and dry skin. 

Moreover, diabetes mellitus may damage the nerves of the body. Also, the increased level of glucose will cause long-term damage to the nerves and may weaken the walls of the blood vessels. 

Nerve Damage: 

Grierson Gopalan syndrome may occur due to any nerve damage or any injuries. The most common cause of this syndrome is peripheral neuropathy. When the sensory nerves which connect the spinal cord and extremities get damaged or injured due to any reason, it causes a burning sensation. The use of toxic drugs, chemotherapy, or heavy medications may cause this. 


Infection is the most common cause of Grierson-Gopalan syndrome. Infections such as Athlete’s foot is mostly seen in people. It is a type of fungal infection, where a person develops the feeling of itching, pain, burning, and tingling in the toes or feet. Such infection may occur due to the wearing of damp shoes, wet socks, or clothes dried in a humid environment. 

Lack Of Nutrition: 

If you have a deficiency of vitamins B12, E, and B5, then you may feel the burning sensation in your feet. So, a lack of nutrition in your body will cause Grierson Gopalan syndrome. 

Stress On Legs: 

When you do any physical activity that involves standing on the legs for a long time, it puts high stress on the feet and thus the feet start causing pain and numbness. And if this continues for a long time, it needs to be treated well. 

Uncomfortable Footwear: 

Any uncomfortable footwear, tight shoes, or ill-fitting sandals may create severe pain in your feet. Also, if you wear footwear with a tough sole, it will put a lot of pressure on your feet and will cause stress, burning, and numbness. 

Miscellaneous Causes: 

Several other conditions may cause this syndrome such as allergies, dermatitis infection, sclerosis, erythromelalgia, and various other associated disorders. 

Treatments Of Grierson-Gopalan Syndrome: 

There are various treatments available for this. You can either treat it by yourself at home by using home remedies tips or can contact a doctor for better consultation. 

Home Remedies: 

To treat GriersonGopalan syndrome in an easier and better way, you can follow the given tips. 

  • Put your feet and soak them in warm water for approximately 15 to 20 minutes. This will give you a relief feeling in your feet. 
  • Do not use cold or hot water to soak your feet.
  • After this, dry and pat the area properly.
  • Now, apply some ointment or antiseptic creams to relieve your pain. 
  • If you have fungal infections in feet such as athlete’s feet, use antifungal lotions, creams, powders, or sprays. 

Contact Doctor: 

If home remedies did not get you rid of pain, contact your doctor. They will prescribe you medications that will help you regain your healthy feet quickly. You can have insulin or any nutritional drugs or Analgesics. Doctors may also prescribe you some antidepressants, antifungal and anticonvulsant drugs. 

So, these are the things that will help you avoid Grierson Gopalan syndrome conditions. Remember all these symptoms and if they occur treat them immediately. In addition to these, always follow physical exercises and therapy to live a healthy life. Keep your diet balanced and wear comfortable padded footwear to avoid burning sensations or foot aches. 

Moreover, avoid wearing dirty socks or wet shoes, and keep your feet clean every time. Similar to your haircare, face care, and health care, your foot needs special care. So, stay healthy, stay safe.